Albumin, Plasma / Fluid

Specimen requirement

Plasma

Fluid

Adult patient:

 Heparin gel tube 

Minimum blood volume: 5 mL

Spot fluid:

Plain bottle

Minimum volume: 10 mL

Paediatric patient:

Paediatric heparin tube

Number of vials: 1

Minimum blood volume: 1.3 mL

Authorisation code required

No

No

24 Hr available service

Yes

 

(Call extension: 3353 for express result)

No

Precaution

Avoid excessive use of tourniquet for sample collection.

 

Patient should be recumbent for at least 1 hour preceding specimen collection.

Method

Spectrophotometry

Reference interval

 

Female: 33 - 48 g/L
Male: 33 - 48 g/L

 

(Source: Australasian Association of Clinical Biochemists (AACB) Harmonised Reference Intervals for Adults (AHRIA). Adult Reference Intervals and Clinical Decision Limits, AACB Harmonisation Workshop July 2013)

Female during pregnancy:
13 - 20 weeks 32 - 43 g/L
21 - 28 weeks 31 - 41 g/L
29 - 34 weeks 30 - 40 g/L
35 - 42 weeks 30 - 40 g/L
During active labour 29 - 41 g/L
Day 1 postpartum 26 - 38 g/L
Day 2 postpartum
27 - 39 g/L


(Source: Klajnbard A et al. Laboratory Reference Intervals during Pregnancy, Delivery and the Early Postpartum Period.  Clin Chem Lab Med. 2010 Feb; 48(2): 237 - 48.)

Clinical indication

Assessment of hydration, nutritional status, protein-losing disorders and liver disease

Result interpretation

Decreased levels may be associated with over-hydration, chronic liver disease, protein losing disorders (e.g. nephrotic syndrome, protein-losing enteropathy), malnutrition, and shifts into the extravascular space (e.g. burns).

 

Decreased levels may also be seen as part of an acute phase response.

 

Increased levels may be seen with dehydration.

 

Increases above the true level may occur with excessive use of tourniquet for sample collection.

 

Erect posture causes a redistribution of body fluids, increasing the plasma albumin concentration.

Measurement of uncertainty

See table.

Frequency of measurement

Daily