Adult patient:
Heparin (no gel) tube [green cap-black ring]
Minimum blood volume: 4 mL
Paediatric patient:
Paediatric heparin tube
Number of vials: 2
Minimum blood volume: 2.6 mL
Authorisation code required
No
24 Hr available service
Yes
(Call extension: 3353 for express result)
Method
Immunoassay (high-sensitivity)
Reference interval
The 99th percentile of cardiac troponin T for normal population is less than 14 ng/L.
(Source:
-
From manufacturer's kit insert.
-
Kristian Thygesen, Joseph S. Alpert, and Harvey D. White. Universal Definition of Myocardial Infarction: the European Society of Cardiology / American College of Cardiology / American Heart Association / World Heart Federation (ESC/ACCF/AHA/WHF) consensus document on Re-definition of Myocardial Infarction. Am J Cardiol. 2007; 50(22): 2175 - 2195)
Reference interval for children:
| < 7 days | ≤ 350 ng/L |
| 8 - 30 days | ≤ 200 ng/L |
| 31 - 120 days | ≤ 100 ng/L |
| 121 days - 1 year | ≤ 30 ng/L |
(Source: from Roche Reference Ranges for Adults and Children: Pre-Analytical Considerations 2008)
Clinical indication
Diagnosis of myocardial infarction
Result interpretation
The assays are specific for a cardiac isoform that occurs only in myocardium.
The test is very specific and sensitive for myocardial damage.
If 1st hsTnT is > 14 ng/L, 2nd hsTnT is recommended at 3 - 6 hrs later to determine % increase from baseline. Diagnosis of acute myocardial infarction is highly suggestive if any hsTnT shows a value > 14 ng/L and a % increase > 100% from baseline.
For paediatric hsTnT reference range, please visit iChemPath@PWH.
Measurement of uncertainty
Frequency of measurement
Daily