Ethanol (Ethyl Alcohol), Serum

 

Synonym Ethyl Alcohol

Specimen requirement

Adult patient:

 

  Clotted blood tube (Serum gel separator clot activator tube)

 

Minimum blood volume: 5 mL

Paediatric patient:

Paediatric clotted blood tube

 

Number of vials: 1

 

Minimum blood volume: 0.8 mL

Authorisation code required

No

24 Hr available service

Yes

Precaution

Do not use alcohol or other volatile disinfectants at the site of venipuncture. Aqueous Zephiran (benzalkonium chloride), aqueous Merthiolate (thimerosal), or povidone-iodine may be used.

Method

Spectrophotometry

Reference interval

 

Slowing of reflexes 10.9 – 21.7 mmol/L
Impaired visual acuity 10.9 – 21.7 mmol/L
Depression of CNS > 21.7 mmol/L
Fatalities reported > 86.8 mmol/L

The above reference values are average values which may be subject to marked between-individual variation.  Habitual heavy drinkers may show more tolerance to the effects of ethanol, non-drinkers less tolerance.

(Source: Tietz NW. Clinical Guide to Laboratory Tests.  3rd ed. Philadelphia.  PA: WB Saunders Co; 1995: 224 - 225)

Clinical indication

To establish recent ingestion of ethanol (e.g. in the assessment of possible drug overdose and impaired consciousness after trauma).

Result interpretation

See reference interval section.

Measurement of uncertainty

See table.

Frequency of measurement

Daily