Gamma Glutamyl Transferase (GGT), Plasma

 

Specimen requirement

Adult patient:

 

  Heparin gel tube

 

Minimum blood volume: 5 mL

Paediatric patient:

 

Paediatric heparin tube

 

Number of vials: 1

 

Minimum blood volume: 1.3 mL

Authorisation code required

No

24 Hr available service

Yes

 

(Call extension: 3353 for express result)

Method

Spectrophotometry

Reference interval

 

Female: < 45 U/L
Male : < 95 U/L

 

(Source: from local population study in 2008)

Clinical indication

Assessment of liver disease

Result interpretation

Increased levels are found in cholestatic liver disease and in hepatocellular disease when there is an element of cholestasis.

 

Levels are increased in diabetes with chronic intake of excess alcohol and with certain drugs (especially phenytoin) as a result of enzyme induction.

 

Pancreatitis and prostatitis may also be associated with increased levels.

Measurement of uncertainty

See table.

Frequency of measurement

Daily