Testosterone (for Male), Serum

 

Specimen requirement

Adult patient (for male only):

 

  Clotted blood tube (Serum gel separator clot activator tube)

 

Minimum blood volume: 5 mL

Paediatric patient:

Paediatric clotted blood tube

 

Number of vials: 2

 

Minimum blood volume: 1.6 mL

Authorisation code required

No

24 Hr available service

No

Method

Immunoassay

Reference interval

Male:

0 - 30 days:

2.6 - 13.9 nmol/L

1 - 5 months: < 6.1 nmol/L
6 - 12 months: < 0.2 nmol/L
1 - 5 years: < 0.9 nmol/L
6 - 9 years: < 1.0 nmol/L
10 - 19 years:  
Tanner stage I   < 0.8 nmol/L
  II   < 2.4 nmol/L
  III   0.5 - 9.7 nmol/L
  IV   3.6 - 18.9 nmol/L
  V   9.2 - 27.8 nmol/L
> 20 years: 9 - 34.7 nmol/L
TETOREI: New reference interval is effective from 18/03/2010

 

 

Source:

Roberts WL et al. Reference Information for the Clinical Laboratory. In Tietz Textbook of Clinical Chemistry and Molecular Diagnostics 4th ed: Elsevier Saunders Missouri, U.S.A.

Clinical indication

Investigation of testicular failure or precocious puberty in males

Result interpretation

Levels are increased in males with precocious puberty.

 

Decreased levels are found in males with testicular failure, either primary or secondary to hypopituitarism.

 

In plasma, testosterone is bound to sex hormone-binding globulin (SHBG), so abnormal levels of SHBG may cause a discrepancy between free and total testosterone.

Measurement of uncertainty

See table.

Frequency of measurement

Daily