Specimen requirement | Adult patient: Clotted blood tube (Clot activator tube) (in ice bath) Minimum blood volume: 6 mL |
Paediatric patient: Paediatric clotted blood tube (in ice bath) Number of vials: 2 Minimum blood volume: 1.6 mL |
|
Authorisation code required | Yes |
24 Hr available service | No |
Precaution |
If the haemoglucostix is < 2.2 mmol/L, take a simultaneous glucose and insulin level.
Send in ice immediately to the laboratory with concurrent plasma glucose. Phone to the laboratory (office hour 2331 / after office hour 3353) before sending the specimen.
Avoid haemolysis, which can lead to spuriously low value. The presence of circulating anti-insulin antibodies and certain insulin analogues (such as aspart, detemir, glargine, glulisine and lispro) may affect the insulin result. |
Method | Immunoassay |
Reference interval |
< 29.1 mIU/L (Source: from manufacturer's kit insert) Footnote: |
Clinical indication | Investigation of fasting hypoglycaemia and insulin resistant states |
Result interpretation |
Increased levels and increased insulin / glucose ratios are found with pancreatic islet beta cell hyperplasia or insulinomas. Non-insulin dependent diabetes mellitus and insulin therapy may also give high levels. To identify self-administration of insulin as a cause of hypoglycaemia, C-peptide assay is also required. |
Measurement of uncertainty | See table. |
Frequency of measurement | 1 - 2 weeks |